Professor Amador Vega highlighted in this lecture how contemporary art has expressed the existential concerns of human beings and, especially, the manifestations of the sacred. Independently to the intellectual debates about the phenomenon of the secularization of modern societies, Vega showed that the work of some significant artists such as Lucio Fontana or Anish Kapoor, beyond their religious confessions, accept the challenge of shaping what has no shape. The ambiguity that architecture, painting or sculpture give to the sacred is also seen in the “silence room” that Antoni Tàpies designed for the Pompeu Fabra University in Barcelona. Vega also payed tribute to Fr. Lluís Duch, who died recently, remarking some central ideas from his thoughts.